Occupational Toxicology

Occupational toxicology represents a discipline among medical specialties that aims to analyze, diagnose and prevent occupational diseases due to chemical and biological hazards in the work environment. These include pollution, carcinogenesis, biological factors, ergonomics, etc (Ref. Groneberg_2006).
Here some examples: It has been seen that benzene causes bone marrow damage and cancer upon long exposure to high concentration (Ref: IARC:chemical). Benzene is metabolized at the hepatic level via CYP P450 leading to the formation of benzene oxide, from which other metabolites are formed. Actually, two minor metabolites such as S-phenyl mercapturic acid and trans, trans-Muconic acid will be present in the urine. These ones need to be monitored in the working environment since they are considered valid biomarkers of the benzene exposure due to their specificity (Sedha_2017).

Eureka offers a solution to this issue by proposing specific kits: the trans, trans-MuconicAcid and S-phenyl mercapturic acid in urine by LC/MS (new kit).

In this section many different kits, which are of a big use in occupational toxicology, are listed.

Butyl Acetate in urine by detector FID or MS (100 tests) Ethyl Acetate in urine by detector FID or MS (100 tests) Isobutyl Acetate in urine by detector FID or MS (100 tests) Methyl Acetate in urine by detector FID or MS (100 tests) Butyl Alcohol in urine by detector FID (100 tests) Isobutyl Alcohol in urine by detector FID(100 tests) Propyl  Alcohol in urine by detector FID (100 tests)  Isopropyl Alcohol in urine by detector FID (100 tests) Methyl-Isobutylketone in urine by detector MS-head space (100 tests) Diethylketone in urine by detector MS-head space (100 tests) trans-1,2-Cyclohexanediol in urine by detector FID or MS (100 tests) Tetrachloroethylene in urine by detector MS-head space (100 tests) Methyltrichloroacetate in urine by detector MS-head space (100 tests) Trichloroethane in urine by detector MS-head space (100 tests) Trichloroethylene in urine by detector MS-head space (100 tests) Trichloroethanol in urine by detector MS (100 tests) Trichloroacetic Acid in urine by detector ECD and/or MS-head space (100 tests) Carbonium Tetrachloride in urine by detector MS-head space (100 tests) Methylene Chloride (Dichloromethane) in urine by detector MS-head space (100 tests) Formic Acid in urine by GC/MS-head space (100 tests) Volatile Organic Compounds (VOC) in urine by GC/MS headspace Volatile Organic Compounds (VOC) in Whole Blood  by GC/MS headspace  Acetates in urine by GC/MS headspace N-Methylacetamide and N-Methylformamide in Urine By GC/MS

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