Special Clinical Chemistry LC/MS

Here, with the expression “Special Clinical Chemistry”, we refer to the analysis of endogenous molecules in body fluids. Blood and urine are the most commonly tested matrices for the determination and quantification of different compounds, like glucose, lipids, proteins, hormones, enzymes and many others. For this aim, several techniques, such as spectrophotometry, immunoassays, and electrophoresis are available. Eureka kits are ready to use kits applied to chromatographic analytical techniques by using several matrices such as urine, plasma, serum, whole blood.
Some of the molecules that need to be analyzed are steroid hormones because any increase or decrease of their level can be the consequence of impaired functioning of endocrine glands. Another important molecule whose plasmatic concentration needs to be monitored is Vitamin D. The monitoring of homocysteine is also essential because it plays a role in the development of cardiovascular disease (Ref Ganguly 2015).Eureka kits represent a valid tool to analyze and quantify endogenous molecules with accuracy, reproducibility, specificity and with a short run of the chromatographic method.

 

 
TUMOR MARKERS
Catecholamines/Metanephrine in plasma by LC/MS –  (96 tests)
(Adrenaline, Noradrenaline, Dopamine, Metanephrine, Normetanephrine, 3-Methoxytyramine)
Free Catecholamines/Free and Total Metanephrine in urine by LC/MS – (100 tests)
(Adrenaline, Noradrenaline, Dopamine, Metanephrine, Normetanephrine, 3-Methoxytyramine)
Free Metanephrine in plasma by LC/MS (extractive Method)
(Metanephrine, Normetanephrine, 3-Methoxytyramine)
VMA, 5-HIAA and HVA in urine by LC/MS –  (100 tests)
 
MARKERS FOR ADRENAL INSUFFICIENCY AND OTHER DESEASES
 
Cortisol and Cortisone in urine by LC/MS –  (100 tests)
Cortisol and Cortisone in urine by LC/MS –  (500 tests) 
 Cortisol and Cortisone in saliva by LC/MS (100 test)
 
Steroid Hormones in serum and plasma by LC/MS (100 tests
(17-OH-Progesterone, Dehydroepiandrosterone (DHEA), Dehydroepiandrosterone sulfate(DHEAS), Androstenedione, Cortisol, 11-Deoxycortisol, Corticosterone, Aldosterone, Testosterone,Dihydrotestosterone, Androsterone, Estrone, Estradiol, Pregnenolone, 17-OH-Pregnenolone, Progesterone, 11-Deoxycorticosterone,  21-Deoxycortisol, Cortisone)
Steroid Hormones in serum and plasma by LC/MS (500 tests)
(17-OH-Progesterone, Dehydroepiandrosterone (DHEA), Dehydroepiandrosterone sulfate(DHEAS), Androstenedione, Cortisol, 11-Deoxycortisol, Corticosterone, Aldosterone, Testosterone,Dihydrotestosterone, Androsterone, Estrone, Estradiol, Pregnenolone, 17-OH-Pregnenolone, Progesterone, 11-Deoxycorticosterone,  21-Deoxycortisol, Cortisone)
Steroid Hormones in serum and plasma by LC/MS – (Extractive Method (100 tests)
(17-OH-Progesterone, Dehydroepiandrosterone (DHEA), Dehydroepiandrosterone sulfate (DHEAS), Androstenedione, Cortisol, 11-Deoxycortisol, Corticosterone, Aldosterone, Testosterone, Dihydrotestosterone, Androsterone, Estrone, Estradiol, Pregnenolone, 17-OH-Pregnenolone, Progesterone, 11-Deoxycorticosterone, 21-Deoxycortisol, Cortisone)
Steroid Hormones in serum and plasma by LC/MS – (Extractive Method (500 tests)
(17-OH-Progesterone, Dehydroepiandrosterone (DHEA), Dehydroepiandrosterone sulfate (DHEAS), Androstenedione, Cortisol, 11-Deoxycortisol, Corticosterone, Aldosterone, Testosterone, Dihydrotestosterone, Androsterone, Estrone, Estradiol, Pregnenolone, 17-OH-Pregnenolone, Progesterone, 11-Deoxycorticosterone, 21-Deoxycortisol, Cortisone)
 
Steroid Hormones in urine by LC/MS
(Cortisol, Aldosterone, Estrone, beta-Estradiol, Cortisone)
 
 
 
ANTIOXIDANT MOLECULES
 
Homocysteine in plasma by LC/MS – (100 tests) 
Homocysteine in plasma by LC/MS –  (500 tests) 
25-OH Vitamin D3 and 25-OH Vitamin D2 in plasma by LC/MS – (100 tests)
25-OH Vitamin D3 and 25-OH Vitamin D2 in plasma by LC/MS – (500 tests)
 
 
BIO MARKER OF VARDIOVASCULAR DESEASES
Trimethylamine N-Oxide (TMAO) in plasma by LC/MS/MS
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